Nanoforms Toxicology
Specialized services for toxicological evaluation and registration of nanomaterials according to REACH regulation.
Nanoforms - New Requirements For REACH
Regulation (EU) 2018/1881 amends REACH to address nanoforms of substances in the registration dossier. Since January 1, 2020, companies must provide additional information on nanomaterials for all registrations, where appropriate. Information to be provided includes:
- Characteristics of nanoforms or sets of nanoforms
- Chemical safety assessment regarding nanoform hazards
- Dossier information requirements
- Downstream user obligations
Depending on manufacturing methods, nanoforms can differ in size distribution, surface shape, and chemistry. These characteristics can affect the behavior and reactivity of each nanoform.
Services for Nanoforms
Technical Services
Assistance in preparing the REACH registration dossier for nanoforms.
- Nanoform identification analysis
- Substance equality profile
- Determination of (eco)toxicological hazards
- Risk assessment of nanoforms
Management Services
Technical assistance for joint submissions, individual companies, and consortia.
- Consortium coordination
- Joint submission management
- Communication with authorities
Research & Development
Support for projects aiming at improvement, reformulation, or seeking new properties.
- Characterization studies
- Specific toxicological research
- Method development
Characteristics of Nanoforms
Key aspects to consider for toxicological evaluation
Size and Distribution
Dimensions and size distribution determine how nanoforms interact with biological systems.
Surface and Chemistry
Morphology and surface treatments significantly affect chemical reactivity and toxicity.
Toxicological Profile
Nanoforms may present distinct toxicological profiles compared to bulk forms.