Toxicological Risk Assessment
Comprehensive solutions to guarantee human health safety and environmental protection.
Our Approach
Risk assessment is the final step in any regulatory program. The result must guarantee the safety of human health and the protection of the environment. At REACH Monitor, we provide exhaustive evaluations based on advanced scientific methodologies and international regulatory standards to ensure the regulatory compliance of your products.
Risk Assessment Process
We apply a comprehensive four-stage methodology to guarantee accurate and complete evaluations.
Hazard Identification
First step to detect potential adverse effects of a substance.
- Rigorous evaluation of existing data
- Advanced method prediction (Read-across)
- QSAR models application
Hazard Characterization
Quantitative evaluation of dose-response effects.
- Dose-level determination (NOAEL, LOAEL)
- Safety threshold calculation (DNEL, PNEC)
- Uncertainty factors analysis
Exposure Assessment
Analysis of real exposure conditions.
- Detailed exposure scenarios
- Implementation of risk management measures
- Advanced modeling (CHESAR, EUSES)
Risk Characterization
Integration of data for a final exhaustive evaluation.
- RCR and MoS calculation
- Product safety conclusions
- Uncertainty analysis
Specialized Services
Regulatory Services
Long-standing experience in risk assessment for various frameworks:
- REACH & BPR
- Pharmaceutical Sector
- Cosmetics and Food/Feed
- Exposure scenarios for mixtures
Research & Development
Scientific partner for innovative R&D projects.
- Design of specific R&D lines
- Alternative substance research
- Experimental test protocols
- Advanced computational simulations